Manchester City

• This will be the first meeting between Manchester City and RB Leipzig in European competition, while Pep Guardiola's side won all four of their games against German opponents in the UEFA Champions League last season (two wins against both Borussia Dortmund and Borussia Monchengladbach).
• Pep Guardiola's side are unbeaten in their last 17 games in the group stage of the UEFA Champions League (W13 D4), with their last such defeat coming in September 2018 versus Lyon. Since Guardiola took charge of Manchester City, they have only lost three of their 30 games in the group stage of the competition (W20 D7).
• City have won 49 of their 90 UEFA Champions League games so far (D16 L25) - they could become the second fastest team to 50 wins in the tournament's history, with Real Madrid the quickest to 50 wins in 88 games, achieved in 2003.

RB Leipzig

• After winning their first two UEFA Champions League games against English opposition (both v Spurs in 2019-20), RB Leipzig have lost three of their last four such fixtures in the competition, including two defeats to Liverpool in 2020-21.
• RB Leipzig have lost three of their previous four away games in the UEFA Champions League (W1), while failing to score in all three defeats; two of which came versus English opponents (0-5 v Manchester United and 0-2 v Liverpool).
• Leipzig defender Marcelo Saracchi continues to rehabilitate following a cruciate ligament tear, while Marcel Halstenberg is nursing an ankle problem.