Granada

• Granada will be the 11th different Spanish side Manchester United have faced in major European competition - they lost their first ever meeting with five of the previous 10 (Athletic Bilbao in 1957, Real Madrid in 1957, Barcelona in 1984, Atlético de Madrid in 1991 and Deportivo de La Coruña in 2001).
• This is Granada's maiden European campaign - they are the first side since RB Leipzig in 2017-18 to reach the quarter-finals of a major European competition in their first European campaign (UEFA Europa League), while the last side to reach the semi-finals in such a season was Villarreal in 2003-04 (UEFA Cup).
• Including qualifying rounds, Yangel Herrera (who is on loan from Manchester City) is Granada's top scorer in European competition this season with five goals.

Manchester United

• Manchester United have reached the quarter-final stages of a major European competition for the 27th time, progressing from 17 of the previous 26. They are winless in the first leg of each of their last three two-legged quarter final matches in Europe (D2 L1).
• United have scored 21 goals in European competition this season, with 13 of them being scored by either Marcus Rashford (seven goals) or Bruno Fernandes (six goals).
• Man United have been rocked by the news that Anthony Martial could miss the remainder of the season with a knee injury, and Marcus Rashford's involvement is up in the air after he came off injured with a knock against Brighton.